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1

Sensitive Detection of Small Molecule–Protein Interactions on a Metal–Insulator–Metal Label-Free Biosensing Platform

Dr. Amir Syahir, Prof. Kotaro Kajikawa, Prof. Hisakazu Mihara

Journal:

Chemistry – An Asian Journal

Year:

2012

Language:

english

File:

PDF, 752 KB

english, 2012

2

Designed Short Peptides that Form Amyloid-Like Fibrils in Coassembly with Amyloid β-Peptide (Aβ) Decrease the Toxicity of Aβ to Neuronal PC12 Cells

Miho Suzuki, Tsuyoshi Takahashi, Junichi Sato, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara

Journal:

Year:

2010

Language:

english

File:

PDF, 630 KB

english, 2010

3

A chromism-based assay (CHROBA) technique for in situ detection of protein kinase activity

Kin-ya Tomizaki, Xu Jie, Hisakazu Mihara

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

4

Sequence dependence in solid-phase-synthesis-cyclization-cleavage for Cyclo(-arginyl-glycyl-aspartyl-phenylglycyl-)

Norikazu Nishino, Ming Xu, Hisakazu Mihara, Tsutomu Fujimoto, Yukio Ueno, Hiromichi Kumagai

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 291 KB

english, 1992

5

Enhanced refractive index sensitivity for anomalous reflection of gold to improve performance of bio-molecular detection

Syahir, Amir, Kajikawa, Kotaro, Mihara, Hisakazu

Journal:

Sensors and Actuators B: Chemical

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

6

Poly(amidoamine)-Dendrimer-Modified Gold Surfaces for Anomalous Reflection of Gold To Detect Biomolecular Interactions

Syahir, Amir, Tomizaki, Kin-ya, Kajikawa, Kotaro, Mihara, Hisakazu

Journal:

Year:

2009

Language:

english

File:

PDF, 1.38 MB

english, 2009

7

A New Optical Label-Free Biosensing Platform Based on a Metal−Insulator−Metal Structure

Syahir, Amir, Mihara, Hisakazu, Kajikawa, Kotaro

Journal:

Year:

2010

Language:

english

File:

PDF, 1.58 MB

english, 2010

8

Anomalous reflection of gold applicable for a practical protein-detecting chip platform

Watanabe, Sinya, Usui, Kenji, Tomizaki, Kin-ya, Kajikawa, Kotaro, Mihara, Hisakazu

Journal:

Molecular BioSystems

Year:

2005

Language:

english

File:

PDF, 384 KB

english, 2005

9

Design of peptides undergoing self-catalytic α-to-β transition and amyloidogenesis

Hisakazu Mihara, Yuta Takahashi, Akihiko Ueno

Journal:

Year:

1998

Language:

english

File:

PDF, 187 KB

english, 1998

10

Design of a Peptide Undergoing α–β Structural Transition and Amyloid Fibrillogenesis by the Introduction of a Hydrophobic Defect

Yuta Takahashi, Akihiko Ueno, Hisakazu Mihara

Journal:

Chemistry - A European Journal

Year:

1998

Language:

english

File:

PDF, 314 KB

english, 1998

11

Construction of α-Helix Peptides with β-Cyclodextrin and Dansyl Units and Their Conformational and Molecular Sensing Properties

Sachiko Matsumura, Seiji Sakamoto, Akihiko Ueno, Hisakazu Mihara

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 377 KB

english, 2000

12

Guest-responsive excimer emission in an α-helix peptide bearing γ-cyclodextrin and two naphthalene units

Takayuki Toyoda, Sachiko Matsumura, Hisakazu Mihara, Akihiko Ueno

Journal:

Macromolecular Rapid Communications

Year:

2000

Language:

english

File:

PDF, 78 KB

english, 2000

13

Photoinduced hydrogen evolution with peptide dendrimer–multi-Zn(II)–porphyrin, viologen, and hydrogenase

Muneyoshi Sakamoto, Toshiaki Kamachi, Ichiro Okura, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2001

Language:

english

File:

PDF, 131 KB

english, 2001

14

Design and synthesis of 3α-helix peptides forming a cavity for a fluorescent ligand

Ikuo Obataya, Seiji Sakamoto, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2001

Language:

english

File:

PDF, 134 KB

english, 2001

15

Heterogeneous Assembly of Complementary Peptide Pairs into Amyloid Fibrils with α–β Structural Transition

Yuta Takahashi, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2001

Language:

english

File:

PDF, 186 KB

english, 2001

16

Nucleobase Amino Acids Incorporated into the HIV-1 Nucleocapsid Protein Increased the Binding Affinity and Specificity for a Hairpin RNA

Tsuyoshi Takahashi, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2002

Language:

english

File:

PDF, 180 KB

english, 2002

17

Cover Picture: ChemBioChem 6/2002

Tsuyoshi Takahashi, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2002

File:

PDF, 19 KB

2002

18

Amyloid Architecture: Complementary Assembly of Heterogeneous Combinations of Three or Four Peptides into Amyloid Fibrils

Yuta Takahashi, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2002

Language:

english

File:

PDF, 511 KB

english, 2002

19

Peptide Design Based on an Antibody Complementarity-Determining Region (CDR): Construction of Porphyrin-Binding Peptides and Their Affinity Maturation by a Combinatorial Method

Mizuki Takahashi, Akihiko Ueno, Hisakazu Mihara

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 305 KB

english, 2000

20

Multipeptide-Metalloporphyrin Assembly on a Dendrimer Template and Photoinduced Electron Transfer Based on the Dendrimer Structure

Muneyoshi Sakamoto, Akihiko Ueno, Hisakazu Mihara

Journal:

Chemistry - A European Journal

Year:

2001

Language:

english

File:

PDF, 214 KB

english, 2001

21

Remarkable Stabilization of the α-Helix Structure by an Intramolecular Host-Guest Bridge in a Cyclodextrin-Peptide Hybrid

Keita Hamasaki, Ryosuke Suzuki, Hisakazu Mihara, Akihiko Ueno

Journal:

Macromolecular Rapid Communications

Year:

2001

Language:

english

File:

PDF, 80 KB

english, 2001

22

Double Naphthalene-Tagged Cyclodextrin-Peptide Capable of Exhibiting Guest-Induced Naphthalene Excimer Fluorescence

Dewi Yana, Tomoko Shimizu, Keita Hamasaki, Hisakazu Mihara, Akihiko Ueno*

Journal:

Macromolecular Rapid Communications

Year:

2002

Language:

english

File:

PDF, 109 KB

english, 2002

23

Fluorescent Cyclodextrin/Peptide Hybrids with a Novel Guest-Responsive Chemosensor in the Peptide Side Chain

Takayuki Toyoda, Hisakazu Mihara, Akihiko Ueno

Journal:

Macromolecular Rapid Communications

Year:

2002

Language:

english

File:

PDF, 348 KB

english, 2002

24

Peptide arrays with designed secondary structures for protein characterization using fluorescent fingerprint patterns

Kenji Usui, Tetsunori Ojima, Mizuki Takahashi, Kiyoshi Nokihara, Hisakazu Mihara

Journal:

Year:

2004

Language:

english

File:

PDF, 582 KB

english, 2004

25

Interactions between peptides containing nucleobase amino acids and T7 phages displaying S. cerevisiae proteins

Sinya Watanabe, Kin-ya Tomizaki, Tsuyoshi Takahashi, Kenji Usui, Kotaro Kajikawa, Hisakazu Mihara

Journal:

Year:

2007

Language:

english

File:

PDF, 390 KB

english, 2007

26

The Fourth Peptide Engineering Meeting (PEM4): Peptide Science and Engineering in Chemical Biology

Hisakazu Mihara

Journal:

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

27

Design and conformational analysis of natively folded β-hairpin peptides stabilized by nucleobase interactions

Ryuichi Uozumi, Tsuyoshi Takahashi, Toshimasa Yamazaki, Viktor Granholm, Hisakazu Mihara

Journal:

Year:

2010

Language:

english

File:

PDF, 981 KB

english, 2010

28

Design, synthesis, and conformation of a model peptide of endothelin with cystine-stabilized α-helix motif

Hisakazu Mihara, Kin-Ya Tomizaki, Norikazu Nishino, Tsutomu Fujimoto, Haruhiko Tamaoki, Yuji Kobayashi

Journal:

Year:

1994

Language:

english

File:

PDF, 419 KB

english, 1994

29

Protein-Detecting Microarrays: Current Accomplishments and Requirements

Kin-ya Tomizaki, Kenji Usui, Hisakazu Mihara

Journal:

Year:

2005

Language:

english

File:

PDF, 614 KB

english, 2005

30

Utilization of L-α-Nucleobase Amino Acids (NBAs) as Protein Engineering Tools: Construction of NBA-Modified HIV-1 Protease Analogues and Enhancement of Dimerization Induced by Nucleobase Interaction

Tsuyoshi Takahashi, Dewi Yana, Hisakazu Mihara

Journal:

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

31

Cover Picture: Protein-Detecting Microarrays: Current Accomplishments and Requirements (ChemBioChem 5/2005)

Kin-ya Tomizaki, Kenji Usui, Hisakazu Mihara

Journal:

Year:

2005

File:

PDF, 37 KB

2005

32

Embedding the Amyloid β-Peptide Sequence in Green Fluorescent Protein Inhibits Aβ Oligomerization

Tsuyoshi Takahashi, Kenichi Ohta, Hisakazu Mihara

Journal:

Year:

2007

Language:

english

File:

PDF, 245 KB

english, 2007

33

Cover Picture: Embedding the Amyloid β-Peptide Sequence in Green Fluorescent Protein Inhibits Aβ Oligomerization (ChemBioChem 9/2007)

Tsuyoshi Takahashi, Kenichi Ohta, Hisakazu Mihara

Journal:

Year:

2007

File:

PDF, 37 KB

2007

34

Cover Picture: Designed Short Peptides that Form Amyloid-Like Fibrils in Coassembly with Amyloid β-Peptide (Aβ) Decrease the Toxicity of Aβ to Neuronal PC12 Cells (ChemBioChem 11/2010)

Miho Suzuki, Tsuyoshi Takahashi, Junichi Sato, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara

Journal:

Year:

2010

File:

PDF, 961 KB

2010

35

Complementary Nucleobase Interaction Enhances Peptide–Peptide Recognition and Self-Replicating Catalysis

Sachiko Matsumura, Tsuyoshi Takahashi, Akihiko Ueno, Hisakazu Mihara

Journal:

Chemistry - A European Journal

Year:

2003

Language:

english

File:

PDF, 291 KB

english, 2003

36

Fabrication of Nanofibers with Uniform Morphology by Self-Assembly of Designed Peptides

Sachiko Matsumura, Shinobu Uemura, Hisakazu Mihara

Journal:

Chemistry - A European Journal

Year:

2004

Language:

english

File:

PDF, 223 KB

english, 2004

37

Design of Peptides That Form Amyloid-Like Fibrils Capturing Amyloid β1–42 Peptides

Junichi Sato, Tsuyoshi Takahashi, Hideo Oshima, Sachiko Matsumura, Hisakazu Mihara

Journal:

Chemistry - A European Journal

Year:

2007

Language:

english

File:

PDF, 498 KB

english, 2007

38

Peptide Nanofibers Modified with a Protein by Using Designed Anchor Molecules Bearing Hydrophobic and Functional Moieties

Ayaka Miyachi, Tsuyoshi Takahashi, Sachiko Matsumura, Hisakazu Mihara

Journal:

Chemistry - A European Journal

Year:

2010

Language:

english

File:

PDF, 538 KB

english, 2010

39

ChemInform Abstract: Construction of HIV Rev Peptides Containing Peptide Nucleic Acid that Bind HIV RRE IIB RNA.

Ichiro Kumagai, Tsuyoshi Takahashi, Keita Hamasaki, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2000

File:

PDF, 24 KB

2000

40

ChemInform Abstract: Construction of Peptides that Undergo Structural Transition from α-Helix to β-Sheet and Amyloid Fibril Formation by the Introduction of N-Terminal Hydrophobic Amino Acids.

Yuta Takahashi, Taro Yamashita, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2000

File:

PDF, 27 KB

2000

41

ChemInform Abstract: Self-Assembly of Polypeptides into Amyloid Fibrils with Structural Transitions.

Hisakazu Mihara, Yuta Takahashi

Journal:

Year:

2002

File:

PDF, 23 KB

2002

42

Complementary Nucleobase Interaction Enhances Peptide—Peptide Recognition and Self-Replicating Catalysis.

Sachiko Matsumura, Tsuyoshi Takahashi, Akihiko Ueno, Hisakazu Mihara

Journal:

Year:

2004

File:

PDF, 51 KB

2004

43

Construction of a multi-functional extracellular matrix protein that increases number of N1E-115 neuroblast cells having neurites

Makiko Nakamura, Masayasu Mie, Hisakazu Mihara, Makoto Nakamura, Eiry Kobatake

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

2009

Language:

english

File:

PDF, 237 KB

english, 2009

44

A Peptide-Cyclodextrin Hybrid System Capable of Detecting Guest Molecules Utilizing Fluorescence Resonance Energy Transfer

Dewi Yana, Tsuyoshi Takahashi, Hisakazu Mihara, Akihiko Ueno

Journal:

Macromolecular Rapid Communications

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

45

Sensing Behavior of Fluorescent Cyclodextrin/Peptide Hybrids Bearing a Macrocyclic Metal Complex

Shuntaro Furukawa, Hisakazu Mihara, Akihiko Ueno

Journal:

Macromolecular Rapid Communications

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

46

Design and synthesis of a polypeptide containing 1-pyrenylalanines as fluorescent probe for four α-Helix bundle structure

Norikazu Nishino, Hisakazu Mihara, Yuji Tanaka, Tsutomu Fujimoto

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 287 KB

english, 1992

47

Efficient preparation of cyclic peptide mixtures by solid phase synthesis and cyclization cleavage with oxime resin

Hisakazu Mihara, Shinji Yamabe, Takuro Niidome, Haruhiko Aoyagi, Hiromichi Kumagai

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 256 KB

english, 1995

48

Construction of a chemically and conformationally self-replicating system of amyloid-like fibrils

Yuta Takahashi, Hisakazu Mihara

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 252 KB

english, 2004

49

Construction of multi-functional extracellular matrix proteins that promote tube formation of endothelial cells

Makiko Nakamura, Masayasu Mie, Hisakazu Mihara, Makoto Nakamura, Eiry Kobatake

Journal:

Year:

2008

Language:

english

File:

PDF, 1.50 MB

english, 2008

50

Screening of α-helical peptide ligands controlling a calcineurin-phosphatase activity

Kenji Usui, Kin-ya Tomizaki, Hisakazu Mihara

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 600 KB

english, 2007